Gm614 Protects Germinal Center B Cells From Death by Suppressing Caspase-1 Transcription in Lupus-Prone Mice
Only a few signaling pathways have been reported in germinal center (GC) B-cell proliferation and death.In this study, we showed that a novel uncharacterized Gm614 protein is highly expressed in GC B cells from lupus-prone mice.Critically, ablation of this GC tonic shower cap B-cell-specific Gm614 promoted GC B-cell death and mitigation of autoimmu